Discovering a drug is one of the most expensive, slowest, and most failure-prone jobs in the world — millions of trials and errors just to land a single medicine. AI Drug Discovery is the attempt to 'jump the queue' at that front end: using computers to predict protein shapes, design molecules, and throw out the ones that don't work before they ever hit the lab. It's the 'picks and shovels' that speeds up the whole pharma industry — but the real thing still has to clear several more gates.
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Theme index· base 100 · USD total return
Why is AI Drug Discovery moving?
Q2 2026
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AI drug discovery surged on deals, funding, and clinical wins
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Pharma dealmaking and IPOs hit record levels US deal value reached $65B in Q1, with record IPOs like Parabilis ($670M) and major partnerships including Insilico–SK Biopharma ($2.5B) and Insilico–Takeda ($600M).
This shows the scale of capital flowing into AI drug discovery through deals and public listings.
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Funding and tech giant backing accelerated Absci raised $100M with Lilly backing, and Nvidia invested in Generate Biomedicines. Nvidia's BioNeMo toolkit expanded adoption, boosting AI drug discovery capabilities.
This highlights both financial and technological support from major players.
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Clinical and commercial milestones achieved Absci reported positive Phase 1 antibody data, Insilico's Rentosertib reached Phase III, and Insilico forecasts H1 profit. Pfizer and J&J deepened AI commitments.
These milestones demonstrate tangible progress and validation of AI in drug development.
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Clinical and legal risks persist Erasca lost $2.8B in market value after a patient death and patent lawsuit, underscoring ongoing clinical and legal uncertainty in AI drug discovery.
This provides a necessary counterweight, showing that risks remain despite overall momentum.
Latest
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AI drug discovery matures: IPOs, big pharma deals, and clinical wins
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AI drug discovery IPOs and funding surge Iambic Therapeutics, backed by Nvidia, filed for a Nasdaq IPO, while Basecamp Research and BigHat Biosciences raised $140M and $75M. These show public and private investors are funding AI drug discovery at scale, giving companies capital to advance pipelines and validating the sector's long-term potential.
Capital access is a key force for the theme, and these new fundraises and IPO filing show strong investor appetite.
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Big pharma expands AI partnerships AbbVie signed a multi-year AI drug discovery deal with Iambic, and four major pharma companies (AbbVie, AstraZeneca, Bristol Myers Squibb, J&J) launched a federated AI model to predict molecule binding. These deals show large drugmakers embedding AI deeper into core discovery, expanding demand for AI platforms.
Pharma partnerships are a direct demand signal for AI drug discovery platforms and validate the technology commercially.
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AI-designed drugs advance toward approval XtalPi submitted an FDA IND for KQTD-126, an AI-designed pan-TRK inhibitor, and its incubated company Viva-Thera nominated an HIV candidate in seven months. These milestones show AI can speed up discovery and move molecules toward clinical testing, strengthening the case that AI works.
Clinical and regulatory progress is the ultimate proof that AI drug discovery can deliver, directly supporting the theme.
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China policy backs AI drug discovery China set a 2030 goal to develop 25% of global first-in-class drugs, explicitly backing AI and quantum computing in drug discovery. The NMPA also strengthened pre-guidance for innovative drugs. This government support expands the market and funding for AI drug discovery, especially in China.
Government policy is a major force shaping the AI drug discovery landscape, and China's plan directly supports the theme.
Q3 2026
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AI drug discovery scaled up in Q3, but new risks emerged
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Investment and efficiency gains July investment topped $2B, with timelines reportedly cut by 70%, and UK biotech financing hit a five-year high. Big pharma also built AI infrastructure, signaling confidence.
Shows strong capital inflow and productivity improvements driving the sector.
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Major deals and commercial progress August brought scaled adoption (BMS–Schrödinger), a $2.2B Pathos licensing deal, Lilly's $40M Absci investment, and Schrödinger's return to profit. September saw Insilico's first Phase 3 trial of a generative-AI-designed drug and more pharma deals.
Highlights concrete commercial validation and clinical milestones that advanced the field.
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Startup fundraising momentum September saw heavy startup fundraising, including Anew Labs' $290M raise and Iambic's IPO, indicating sustained investor appetite for AI-driven drug discovery ventures.
Demonstrates continued capital access for emerging players, fueling innovation.
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New operational and competitive risks Risks mounted: Alphabet disbanded its AlphaFold team, validation labs became a bottleneck, chip shortages constrained compute, and Anthropic entered wet-lab biology as a deep-pocketed competitor.
Presents real counterweights that could slow progress and increase competition.
News & notes movingAI Drug Discovery
United States
AI Drug Discovery▲
Profluent and BioMarin Partner to Design Novel Enzyme Therapies Using AI
Profluent announced a collaboration with BioMarin Pharmaceutical Inc. to design and optimize novel enzyme therapies for BioMarin's pipeline. Under the agreement, Profluent will apply its foundational AI models to generate novel potential drug candidates, and BioMarin will screen the results with the goal of eventually advancing the most promising designs. Profluent will design and optimize enzyme candidates using its suite of proprietary protein language models, which draw on the Profluent Protein Atlas, described as the largest protein sequence dataset in the world with more than 115 billion unique sequences. BioMarin will use Profluent's AI models to rapidly explore protein designs and identify candidates with desired activity and stability profiles, then advance the most promising into preclinical testing. Pooja Agarwal, Vice President and Head of Metabolic Conditions Research at BioMarin, said the collaboration pairs Profluent's de novo protein design approach with BioMarin's decades of enzyme therapy expertise, while Profluent CEO Ali Madani said the partnership aims to accelerate BioMarin's drug discovery pipeline.
Biotech & Genomic Medicine › AI Drug Discovery ▲Technology
Biotech & Genomic Medicine › Rare Disease Technology
BMRN · Technology · Positive BioMarin partners with Profluent to use AI protein design to generate and optimize novel enzyme therapy candidates for its pipeline.
Profluent · Technology · Positive Profluent's AI protein language models will be applied to design novel enzyme candidates in a collaboration with BioMarin.
Oracle Launches Fusion Claw With 25 New Agentic Applications
Oracle unveiled Fusion Claw, a new offering that combines AI reasoning with enterprise computation, alongside 25 new agentic applications that can reason, compute, adapt and execute specialist-grade work. The company said Fusion Claw is designed to let highly complex work be completed more autonomously at scale, and Oracle EVP of Applications Development Chris Leone will discuss the offering on NYSE Live. Separately, Envisagenics is partnering with Boehringer Ingelheim to identify precision cancer targets and develop therapies for hard-to-treat solid tumors, with Envisagenics Co-founder and CEO Maria Luisa Pineda appearing on NYSE Live to explain how the collaboration advances precision medicine. In markets, the U.S. 10-year Treasury yield ended Monday above 5.2% as investors await the August PCE Price Index and the September jobs report, and more than 70% of traders expect the Fed to raise interest rates in October, according to the latest data. Bloom Energy celebrated its 25th anniversary of founding at the Opening Bell, while Vanguard marked the launch of three new ETFs at the Closing Bell.
Artificial Intelligence › AI Applications & Copilots ▲Technology
Artificial Intelligence › Agentic AI & Autonomous Workflows ▲Technology
Biotech & Genomic Medicine › AI Drug Discovery Technology
ORCL · Technology · Positive Oracle unveiled Fusion Claw combining AI reasoning with enterprise computation plus 25 new agentic applications.
Boehringer Ingelheim International GmbH · Demand · Positive Boehringer Ingelheim is partnering with Envisagenics to identify precision cancer targets and develop therapies for hard-to-treat solid tumors.
Envisagenics · Demand · Positive Envisagenics is partnering with Boehringer Ingelheim to identify precision cancer targets and develop therapies for hard-to-treat solid tumors.
United StatesGermanyNetherlandsJapanUnited Kingdom
AI Drug Discovery▲
AbbVie, argenx, Lundbeck and Takeda Join Antibody Developability Consortium
Ginkgo Datapoints, an offering of Ginkgo Bioworks, and Apheris GmbH announced that the Antibody Developability Consortium has launched with AbbVie, argenx, Lundbeck, and Takeda as founding members. The industry collaboration aims to build the field's largest standardized antibody developability dataset, with each founding member contributing proprietary antibody sequences and Ginkgo Datapoints filling any remaining capacity from publicly available sources to reach 10,000 antibodies in total. Using Apheris' federated infrastructure, members can train, benchmark, and refine AI models on the full consortium dataset without exposing their raw proprietary sequences to other members, and they retain ownership of the sequences and assay data they contribute. Ginkgo Datapoints leads the scientific design and execution, including sequence selection, antibody production, and high-throughput wet-lab characterization, and trains a foundation antibody developability model within Apheris' secure environment. Charlotte Deane of the University of Oxford and Peter Tessier of the University of Michigan will provide independent scientific oversight, and the consortium's initial dataset is targeted for delivery to members by early 2027.
Biotech & Genomic Medicine › AI Drug Discovery ▲Technology
Biotech & Genomic Medicine › Autoimmune & Immunology Therapeutics Technology
DNA · Demand · Positive Ginkgo Datapoints leads the consortium's scientific design and execution, gaining a major industry collaboration with four pharma founding members.
Apheris · Demand · Positive Apheris provides the federated infrastructure enabling consortium members to train AI models without exposing proprietary sequences.
0ABR.LSE · Technology · Positive Lundbeck joins as founding member of the consortium, contributing proprietary antibody sequences to advance AI developability models.
4502.JP · Technology · Positive Takeda joins as founding member of the Antibody Developability Consortium, contributing proprietary antibody sequences for AI model training.
ABBV · Technology · Positive AbbVie joins as founding member of the Antibody Developability Consortium, contributing proprietary antibody sequences to build a standardized developability dataset and AI models.
AI drug development commercialization advances, ESMO annual meeting features 28 China-led breakthrough studies
The commercialization of AI-driven drug development continues to move forward. Insilico Medicine announced a partnership to build a generative biology foundation model focused on biologic design and target optimization. The 2026 European Society for Medical Oncology annual meeting will open from October 23 to 27, featuring 28 breakthrough clinical studies led by or deeply involving China, of which 4 were selected for oral presentation in the plenary session, accounting for one-third of the total. In the pharmaceutical segment, 29 late-breaking abstract trial drugs were originally developed or co-developed by domestic Chinese pharmaceutical companies, covering multiple frontier areas including antibody-drug conjugates, bispecific antibodies, and EGFR-TKI-resistant non-small cell lung cancer. Guosheng Securities noted that the radiopharmaceutical sector recently saw two major deals: Telix acquired ITM for 1.65 billion US dollars, and Borui Chuanghe signed a collaboration with Novartis worth up to 900 million US dollars. Meanwhile, Ionis' oligonucleotide therapy Ulefnersen met its primary endpoint in a Phase III study for FUS-ALS, providing the first effective treatment option for this rare disease. As of August 31, 2026, the top ten weighted stocks in the SSE STAR Market Biomedical Index accounted for 51.54% of the total, namely United Imaging Healthcare, BeiGene, Allist Pharmaceuticals, Baili Tianheng, Zelgen Biopharmaceuticals, RemeGen, iRay Technology, Huitai Medical, Junshi Biosciences, and MGI Tech.
Biotech & Genomic Medicine › Oncology Therapeutics ▲Technology
Biotech & Genomic Medicine › AI Drug Discovery ▲Technology
Biotech & Genomic Medicine › Antibody-Drug Conjugates (ADC) ▲Technology
3696.HK · Technology · Positive Insilico Medicine announced a partnership to build a generative biology foundation model for biologic design and target optimization.
IONS · Technology · Positive Ionis' Ulefnersen met its primary endpoint in a Phase III FUS-ALS study, the first effective treatment for this rare disease.
Boruichuanghe · Demand · Positive Borui Chuanghe signed a collaboration with Novartis worth up to $900 million.
ITM Isotope Technologies Munich SE · Capital · Positive Telix acquired ITM for $1.65 billion, a valuation/M&A event for the radiopharmaceutical company.
NOVN.SW · Demand · Positive Novartis signed a collaboration with Borui Chuanghe worth up to $900 million, a deal that expands its pipeline.
Novo Nordisk Signs Up to $1.4 Billion Oral Drug Deal With Orbis Medicines
Novo Nordisk has signed a drug-discovery and licensing agreement with Orbis Medicines worth up to $1.4 billion to develop oral therapies for cardiometabolic diseases traditionally treated with injections. The deal includes upfront and potential development and commercial milestone payments, tiered royalties on future sales, and a strategic investment by Novo in Orbis, though the companies did not disclose the size of the upfront payment, the investment, or the breakdown of the $1.4 billion headline value. The collaboration will use Orbis' AI-enabled nGen platform to discover orally bioavailable macrocycles, which Orbis said have achieved up to 18% oral bioavailability in preclinical work. The agreement gives Novo another route to expand its oral cardiometabolic pipeline beyond its existing Wegovy pill, at a time when Reuters reported Novo expects oral treatments to account for more than one-third of GLP-1-based obesity therapies by 2030. Much of the $1.4 billion is tied to future milestones rather than an immediately disclosed cash payment, and the collaboration remains at the discovery stage, so the immediate earnings and cash-flow contribution is likely to be limited as Novo seeks to rebuild its pipeline after warning that 2026 sales and operating profit could decline by as much as 13%.
Biotech & Genomic Medicine › Metabolic, Diabetes & Obesity ▲Demand
Biotech & Genomic Medicine › AI Drug Discovery Technology
NVO · Technology · Positive Novo signs up to $1.4B licensing deal with Orbis to develop oral cardiometabolic therapies using Orbis' AI-enabled nGen macrocycle platform, expanding its oral pipeline beyond the Wegovy pill.
Orbis Medicines · Capital · Positive Orbis receives upfront and potential milestone payments plus tiered royalties and a strategic investment from Novo under the drug-discovery and licensing agreement.
AbbVie and Iambic Launch Multi-Year AI Drug Discovery Collaboration
AbbVie Inc. and Iambic announced a multi-year collaboration to use Iambic's AI platform to accelerate small-molecule drug discovery across immunology, neuroscience, and oncology. The partnership will use Iambic's Enchant v3 model, which is trained on more than 6,000 molecular properties and is designed to evaluate multiple drug characteristics simultaneously, with the companies pursuing candidates with first-in-class and best-in-class potential. Iambic will receive an upfront payment, milestone payments, and tiered royalties on net sales, though the financial terms were not disclosed. The deal comes as AbbVie leans on newer products to offset Humira's decline: in the first half of 2026, Skyrizi generated $9.99 billion, up 27.3%, and Rinvoq generated $4.64 billion, up 24.0%, while Humira revenue fell 37.3% to $1.44 billion, and Vraylar revenue rose 18.7% to $1.98 billion. AbbVie's second-quarter 2026 revenue reached $16.99 billion, up 10.2%, with Skyrizi and Rinvoq together generating $8.03 billion, up roughly 24% year over year, and its 2025 filing says U.S. composition-of-matter patents for Skyrizi and Rinvoq are expected to expire in 2033. The collaboration carries no immediate earnings catalyst, since any royalties or product revenue depend on successful discovery, clinical development, and regulatory approval, and AbbVie would share economics through milestone payments and tiered royalties if Iambic's models produce successful medicines.
Biotech & Genomic Medicine › AI Drug Discovery ▲Technology
Biotech & Genomic Medicine › Autoimmune & Immunology Therapeutics Technology
ABBV · Technology · Positive AbbVie launches a multi-year AI drug discovery collaboration with Iambic to accelerate small-molecule candidates in immunology, neuroscience, and oncology.
Iambic Therapeutics · Demand · Positive Iambic's AI platform is chosen by AbbVie for a multi-year collaboration, bringing upfront, milestone, and royalty payments.
Roche Signs AI Drug Discovery Deals With Earendil Labs and Atavistik Bio
Roche Holding announced new R&D alliances focused on AI-powered therapeutics and metabolic disease programs in late September 2026. The group signed a research partnership with Earendil Labs to apply AI to bispecific antibody cancer therapies across multiple tumor types, and agreed a collaboration with Atavistik Bio to pursue allosteric small molecules for cardiovascular, renal and metabolic conditions. Enicepatide, also known as CT-388, reported positive Phase 2 results in type 2 diabetes and obesity, highlighting Roche's GLP-1/GIP pipeline ambitions. The company's late stage pipeline includes 10 new molecular entities moving into Phase III and the potential launch of up to 19 medicines by the end of the decade, and the full story points toward a CHF370 fair value for Roche Holding. Analysts still flag execution and pricing pressure, especially in China and in obesity where Eli Lilly and Novo Nordisk are strong competitors.
Biotech & Genomic Medicine › AI Drug Discovery ▲Technology
Biotech & Genomic Medicine › Metabolic, Diabetes & Obesity ▲Demand
Biotech & Genomic Medicine › Oncology Therapeutics Technology
Biotech & Genomic Medicine › Antibody-Drug Conjugates (ADC) Technology
Biotech & Genomic Medicine › Rare Disease Technology
ROP.SW · Technology · Positive Roche signed AI drug discovery deals with Earendil Labs and Atavistik Bio and reported positive Phase 2 results for enicepatide/CT-388.
ROP.SW · Competition · Negative Analysts flag execution and pricing pressure, especially in China and obesity where Eli Lilly and Novo Nordisk are strong competitors.
Atavistik Bio · Technology · Positive Atavistik Bio agreed a collaboration with Roche to pursue allosteric small molecules for cardiovascular, renal and metabolic conditions.
Earendil Labs · Technology · Positive Earendil Labs signed a research partnership with Roche to apply AI to bispecific antibody cancer therapies across multiple tumor types.
AMD Partners With Advantech and MindWalk on Edge AI and Life Sciences
Advanced Micro Devices announced a collaboration with Advantech to accelerate Edge AI workloads using AMD embedded and GPU platforms, while MindWalk has moved OpenFold3 into production on AMD Instinct GPUs. The Advantech alliance focuses on scalable, partner-led Edge AI solutions, with Advantech's WEDA ecosystem putting AMD Ryzen AI Embedded processors into pre-validated edge platforms that can be rolled out across industrial fleets. MindWalk's OpenFold3 work on Instinct MI325X GPUs reaches into life sciences prediction workloads, supported by inference microservices for regulated, production-grade scientific use cases. The company said the announcements line up with its existing narrative of expanding AI infrastructure across accelerators, software and full systems, and that MindWalk's validation of AMD Inference Microservices and the Kubernetes native path into regulated production supports the view that ROCm and related tooling can lower switching costs for third party models. AMD investors are watching how many additional production case studies using AMD Instinct GPUs and inference microservices appear through 2027 across sectors like life sciences, security and edge industrial systems.
Biotech & Genomic Medicine › AI Drug Discovery Technology
Robotics & Physical AI › Industrial Automation & Cobots Technology
AMD · Technology · Positive AMD announced Advantech Edge AI collaboration using Ryzen AI Embedded processors and MindWalk's OpenFold3 production on Instinct MI325X GPUs, expanding its AI hardware/software ecosystem.
2395.TW · Technology · Positive Advantech is partnering with AMD to put Ryzen AI Embedded processors into pre-validated WEDA edge platforms for scalable Edge AI deployments.
XtalPi Submits FDA IND for KQTD-126, First Gut-Restricted Pan-TRK Inhibitor
XtalPi has submitted an Investigational New Drug application to the U.S. Food and Drug Administration for KQTD-126, a potential first-in-class gut-restricted pan-TRK inhibitor for chronic intestinal pain associated with irritable bowel syndrome and inflammatory bowel disease. The candidate is the first program from XtalPi's proprietary pipeline to reach an IND submission since the portfolio was unveiled in the company's recent interim results. In preclinical studies, KQTD-126 achieved pan-TRK inhibition at sub-nanomolar concentrations, with an IC50 below 1 nM, and a gut tissue-to-blood exposure ratio exceeding 1,000 to 1, confining activity to the gastrointestinal tract to limit systemic exposure and avoid the neurological side effects of systemic TRK inhibitors. XtalPi said the compound was designed using its generative and predictive AI models integrated with automated chemistry robots, a closed-loop process of computational design, automated synthesis, screening, and molecular refinement. IBS affects approximately 10% to 15% of the global population, while more than 10 million people live with IBD, and BCC Research projects the global IBS and IBD therapeutics market will reach US$52.6 billion by 2030.
Biotech & Genomic Medicine › AI Drug Discovery ▲Technology
Biotech & Genomic Medicine › Rare Disease Demand
Artificial Intelligence › AI Applications & Copilots Technology
2228.HK · Technology · Positive XtalPi submitted an FDA IND for its AI-designed first-in-class gut-restricted pan-TRK inhibitor KQTD-126, advancing its proprietary pipeline.
Recursion Pharmaceuticals Touts Over $500 Million in Partner Payments, Cash Runway Into Early 2028
Recursion Pharmaceuticals has received more than $500 million in upfront and milestone payments from its portfolio of pharma, technology and data partnerships as of the second quarter of 2026, with cash, cash equivalents and restricted cash totaling $556.8 million at the end of June and a runway the company expects to extend into early 2028 without additional financing. Through its Bayer collaboration, Recursion is advancing precision oncology programs and is eligible for up to $1.5 billion in potential development and commercial milestones plus tiered royalties, while its partnerships with Roche and its wholly-owned subsidiary Genentech cover neuroscience and gastrointestinal oncology and could support up to 40 programs, each potentially generating more than $300 million in milestones plus tiered royalties. In the second quarter of 2026, Genentech advanced the first neuroscience target from the collaboration into early discovery, and partnerships with Sanofi and Merck KGaA offer up to $5.2 billion and $674 million respectively in potential milestone payments in addition to royalties. Recursion has also strengthened its AI infrastructure, with its NVIDIA partnership supporting the development of BioHive-2 and its 2024 combination with Exscientia enhancing computational chemistry and automated drug-design capabilities, and by August 2026 it had built and curated more than 50 petabytes of multimodal data. Technology and data partnerships with Google Cloud, Helix, Tempus and HealthVerity further broaden its platform, while competitors Relay Therapeutics and Schrödinger continue to build their own pipelines, and RXRX shares have lost 9.6% year to date against the industry's 8.5% growth, with 2026 loss estimates narrowing from $1.01 to 94 cents per share over the past 60 days.
BigHat Biosciences Raises $75 Million Series C to Advance AI-Designed Therapeutics
BigHat Biosciences announced the completion of a $75 million Series C financing, bringing its total funding raised to date to $223 million. The round was co-led by DFJ Growth and Premji Invest, with participation from Catalio Capital Management, LG Technology Ventures, Sigmas Group, and existing investors including 8VC, Alexandria Venture Investments, Amgen Ventures, Andreessen Horowitz, Discovery Ventures, GRIDS Capital, Intermountain Ventures, Eli Lilly and Company, Merck Global Health Innovation Fund, Quadrille Capital, and Section 32. Proceeds will support growth of BigHat's platform for rapid data generation to power frontier intelligence for protein design and advancement of its pipeline of AI-designed therapeutics, including BHB810 and BHB299, to key clinical readouts. BHB810, a CDH17-directed antibody-drug conjugate for gastric cancer and other advanced gastrointestinal tumors, is one of the first AI-driven biologics to reach humans and has begun dosing patients in a Phase 1 trial, while BHB299, an avidity-driven T-cell engager targeting CEACAM6-expressing solid tumors, is nearing completion of preclinical development with human trials planned for 2027. The financing follows the company's $80 million Series B in 2022 and a $44 million Series B extension in 2025, and comes as BigHat has forged collaborations with Amgen, Merck, Johnson & Johnson, AbbVie and Lilly.
InnoCare Signs Licensing Deal With Eli Lilly Worth Up to $3.35B
InnoCare Pharma has entered a research collaboration and license agreement with Eli Lilly to develop new medicines, the companies said on Thursday. Under the deal, InnoCare will use its drug discovery platform and research to discover and advance compounds against up to five targets. InnoCare is eligible to receive up to $100M in upfront and near-term payments, plus milestone-based payments of up to $3.25B contingent on development and commercial achievements. The company will also be eligible for single-digit tiered royalties based on annual net product sales.
Biotech & Genomic Medicine › AI Drug Discovery Competition
688428.CG · Capital · Positive InnoCare signs licensing deal with Eli Lilly worth up to $3.35B, including up to $100M upfront and $3.25B in milestones plus royalties.
LLY · Capital · Positive Eli Lilly signs licensing deal with InnoCare worth up to $3.35B to develop new medicines against up to five targets.
Arcturus Reports Positive Interim Phase 2 Results for ARCT-810 in OTC Deficiency
Arcturus Therapeutics said interim phase 2 results for ARCT-810 showed the candidate reduced and/or maintained first morning fasting ammonia within the normal range in patients with ornithine transcarbamylase deficiency, and also reduced glutamine, with some individuals reaching the normal range. Based on those results and a June meeting with the US FDA, the company aims to begin dosing of ARCT-2601 close to the end of the year in participants 12 years and older under an amended phase 2 protocol that integrates ARCT-2601 into the current ARCT-810 phase 2 study. Both ARCT-810 and ARCT-2601 are mRNA therapeutics for OTC deficiency, but ARCT-810 uses the LUNAR platform while ARCT-2601 uses the next-generation LUNAR 2.0 platform, which Arcturus says produces greater than 30-fold higher protein expression and could allow for lower or less frequent dosing. OTC deficiency is a rare genetic disorder in which the body stops breaking down and removing nitrogen, leading to dangerous ammonia levels in the blood. Arcturus is also acquiring AI discovery company myNeo, with which it has worked since 2024, and the deal is expected to close in October.
Biotech & Genomic Medicine › mRNA Platforms ▲Technology
Biotech & Genomic Medicine › Rare Disease ▲Demand
Biotech & Genomic Medicine › AI Drug Discovery Technology
ARCT · Technology · Positive Interim Phase 2 results show ARCT-810 reduced/maintained normal fasting ammonia and glutamine in OTC deficiency, supporting advancement to ARCT-2601 dosing.
ARCT · Capital · Positive Arcturus is acquiring AI discovery company myNeo, with the deal expected to close in October.
myNeo · Capital · Positive myNeo is being acquired by Arcturus, with the deal expected to close in October.
Iambic Therapeutics Files for US IPO, Announces AbbVie Collaboration
Iambic Therapeutics filed for a U.S. IPO on September 21 after raising money from NVIDIA Corporation and Qatar Investment Authority, and the same day announced a multi-year research collaboration with AbbVie Inc. Under the agreement, AbbVie can use Iambic's Enchant platform to design small-molecule programs across immunology, neuroscience and oncology, with the deal including a $40 million upfront payment, up to $670 million in development and sales-based milestones across the two collaboration targets, and tiered royalties ranging from the mid-single digits to the low teens. AbbVie entered the collaboration from a position of operating strength, with Q2 2026 revenue of about $16.99 billion as Skyrizi and Rinvoq helped offset legacy Humira erosion. NVIDIA, meanwhile, stands to benefit as drug-design startups consume accelerated compute for training, simulation and inference, though even a successful biotech investment is tiny relative to its data-center business. The IPO will expose investors to the riskiest layer of the AI drug discovery value chain directly, while ABBV and NVDA offer more diversified ways to watch the same thesis.
Biotech & Genomic Medicine › AI Drug Discovery ▲Technology
Biotech & Genomic Medicine › Autoimmune & Immunology Therapeutics Technology
Artificial Intelligence › AI Compute & Accelerator Silicon ▲Demand
Iambic Therapeutics · Demand · Positive Iambic files for a US IPO and announces a multi-year AbbVie collaboration using its Enchant platform, including $40M upfront and up to $670M in milestones.
ABBV · Demand · Positive AbbVie signs multi-year collaboration with Iambic to design small-molecule programs across immunology, neuroscience and oncology, with $40M upfront and up to $670M in milestones.
NVDA · Demand · Positive NVIDIA stands to benefit as drug-design startups like Iambic consume accelerated compute for training, simulation and inference.
Basecamp Research Raises $140M Series C to Advance AI-Designed Therapeutics
Basecamp Research has raised a $140M Series C financing to train a new generation of EDEN models and advance a pipeline of AI-designed therapeutics toward clinical development. The oversubscribed round was led by S32, with participation from Anthropic's Anthology Fund, Catalio Capital Management, European Tech Collective, Firebrand River Capital, Inception Fund, King Philanthropies, NATO Innovation Fund, NVIDIA, PostScriptum, Redalpine, The Rockefeller Foundation, Singular, Sovereign AI and True Ventures, plus additional investment from senior leaders across pharma, biotech and global industry including André Hoffmann, Vice-Chairman of Roche. The London- and Boston-based company is applying EDEN, its biological foundation model, to in vivo cell therapy, pairing the model's ability to design long and complex DNA sequences with large serine recombinases that can precisely integrate them into the genome, an approach it says could transform treatment of cancer and autoimmune disease. Basecamp has demonstrated strong preclinical results across multiple modalities and disease areas, and has appointed Richard Pearce, formerly of Biogen, as Chief Business Officer to expand its pharmaceutical partnerships. Andy Conrad, General Partner at S32 and former CEO of Google's Verily, joins the Board of Directors. EDEN models are trained on the Trillion Gene Atlas, which Basecamp calls the world's largest proprietary biological AI training dataset, built with partners including NVIDIA, Anthropic, PacBio and Ultima Genomics and drawing on data collected through access and benefit-sharing partnerships in more than 30 countries across all seven continents.
Artificial Intelligence › Foundation Models & Research Labs Capital
Artificial Intelligence › AI Tooling, Data & MLOps Technology
Basecamp Research · Capital · Positive Basecamp Research raised a $140M oversubscribed Series C to train EDEN models and advance its AI-designed therapeutics pipeline.
NVDA · Capital · Positive NVIDIA participates in Basecamp Research's $140M Series C and co-built the Trillion Gene Atlas training dataset.
Anthropic · Capital · Positive Anthropic's Anthology Fund participated in Basecamp Research's $140M Series C round.
Oracle Launches Life Sciences Data Intelligence Platform With 122 Million Patient Records
Oracle has launched Oracle Life Sciences Data Intelligence, a cloud native platform that combines real-world data, domain-trained AI capabilities, and advanced analytics in a single connected environment for pharmaceutical research teams. The platform's data foundation includes Oracle Health Real-World Data, comprising more than 122 million de-identified patient records, and lets researchers use natural language to explore and refine patient cohorts, perform outcome analyses, and automate multistep research workflows. Seema Verma, executive vice president and general manager of Oracle Health and Life Sciences, said fragmented data and disconnected workflows continue to slow the path to discovery, and that Oracle's combination of real-world data and domain-specific AI tools helps researchers conduct studies and explore data in natural language. The solution, formerly known as Oracle Life Sciences AI Data Platform, unifies customer, third-party, and Oracle Health data in a secure environment with enhanced data governance, and is designed to work across Oracle's broader ecosystem including OCI, Oracle Life Sciences, Oracle Fusion Cloud applications, and Oracle Health solutions. Dr. Nimita Limaye, Research Vice President for Life Sciences R&D Strategy and Technology at IDC, said AI is an operational imperative for the industry that creates value only when researchers can trust it, and that Oracle is bridging that gap by turning complex research questions into credible evidence faster.
Cloud & Digital Infrastructure › Data Platforms & Analytics ▲Technology
Biotech & Genomic Medicine › AI Drug Discovery Technology
Artificial Intelligence › AI Applications & Copilots Technology
ORCL · Technology · Positive Oracle launched its Life Sciences Data Intelligence platform combining 122M patient records with domain-trained AI for pharma research.
ProQR Appoints Chris Hart as Chief Data and AI Officer, Thomas Wolf as Board AI Advisor
ProQR Therapeutics N.V. announced the appointment of Chris Hart as Chief Data and AI Officer and Thomas Wolf to its Board of Directors as strategic AI advisor, moves the company said will support its strategy to scale AI across drug discovery and development using its Axiomer RNA editing platform. Hart most recently served as Vice President of Data Science and AI/ML at Eli Lilly and Company and brings more than two decades of experience in computational biology, genomics, AI and oligonucleotide drug development, including more than 15 years focused on AI/ML-driven optimization of oligonucleotide therapeutics. Wolf is co-founder and Chief Science Officer of Hugging Face, the open-source AI platform that Nvidia recently agreed to acquire for $12.9B. ProQR said its AI-enabled discovery process identified AX-0811, its first program in clinical testing, which achieved approximately 60% editing efficiency in humanized models, around six-fold higher than the prior generation AX-0810, with reduced discovery timelines from three years to approximately three months. The company expects up to 5 clinical data readouts over the next 12 months across 4 development programs, with target engagement data from the first two cohorts of AX-0811 expected in early January 2027, and additional programs including AX-0422 for MPS I Hurler syndrome and AX-2911 for PNPLA3-associated MASH progressing toward the clinic.
AbbVie Wins EU Approval for RINVOQ in Pediatric Arthritis
AbbVie received European Commission approval for RINVOQ in polyarticular juvenile idiopathic arthritis for patients as young as two. The company also launched AA Signature SKIN360 in the U.S. through Allergan Aesthetics, a multimodal digital platform for medical aesthetics consultations, and entered AI-focused collaborations with Iambic and the AISB Bind project to apply advanced models to drug discovery and molecular binding prediction. AbbVie, a research-focused biopharmaceutical group with a market value of about $467.4b, is using these moves to extend from core medicine development into digital tools and patient-facing services. The RINVOQ pediatric extension, the AA Signature SKIN360 rollout and the new AI partnerships are only part of AbbVie's broader story, with the company pointing to diversified growth beyond Humira. Follow-through markers include RINVOQ uptake in European pediatric arthritis treatment data, early output from the Iambic and AISB Bind collaborations such as disclosed preclinical candidates, and digital aesthetics usage updates when AbbVie next reports segment performance or holds its 2027 guidance discussions.
Biotech & Genomic Medicine › Autoimmune & Immunology Therapeutics ▲Regulation
Biotech & Genomic Medicine › AI Drug Discovery Technology
ABBV · Regulation · Positive European Commission approval extends RINVOQ to pediatric polyarticular juvenile idiopathic arthritis patients as young as two.
ABBV · Technology · Positive AbbVie launched the AA Signature SKIN360 digital aesthetics platform and entered AI drug-discovery collaborations with Iambic and the AISB Bind project.
Iambic Therapeutics · Technology · Positive Iambic is named as an AI-focused collaboration partner applying advanced models to drug discovery for AbbVie.
Goldman Sachs Starts Tempus AI at Neutral With $75 Target
Goldman Sachs initiated coverage of Tempus AI with a Neutral rating and a $75 price target on September 21, flagging renewal risk in the company's data business even as diagnostics growth stays visible. The call landed the same day Tempus announced an extension of its partnership with Recursion Pharmaceuticals through 2029, replacing potentially discretionary fees with $42 million of committed payments. Tempus generated $382.5 million of second-quarter revenue, up 22% year-over-year, with Diagnostics revenue up 20% to $289.3 million, oncology volumes up 31%, and MRD testing at 9,000 tests, up 38% from the prior quarter. The Data and Applications segment grew faster, with revenue up 28% in the quarter and Insights revenue up 36%, alongside roughly $200 million in new Data and Applications licenses signed during the quarter. Management estimates FDA approval of tumor-only xT CDx could add about $85 million of annual revenue beginning in 2027, while the company also received FDA clearance for a third cardiovascular AI product and was selected for an ARPA-H program worth up to $9.5 million. Short interest stood at 29.46 million shares, or 29.17% of the float, down from 33.23 million a month earlier, while ARK Investment Management raised its stake 5% to 10.02 million shares and Citadel expanded its position 318% to 2.51 million shares.
XtalPi-Backed Viva-Thera Nominates HIV-1 MPER PCC in Seven Months
XtalPi announced that Viva-Thera, a biotechnology company it incubated and backs as a strategic shareholder, has nominated a preclinical candidate targeting the membrane-proximal external region of HIV-1 gp41, completing discovery and optimization in seven months by combining Viva-Thera's atomic-resolution structural research with XtalPi's AI drug design and automation platform. Deploying generative AI from the outset, XtalPi navigated a chemical space of approximately 10 million compounds to isolate five validated hits with desirable drug properties and strong antiviral activity, then continuously optimized the leads to reach PCC nomination. The asset targets gp41-mediated membrane fusion at MPER, a region that retains approximately 90% sequence identity across viral strains, opening a path toward a broad-spectrum antiviral with a binding site distinct from those addressed by reverse-transcriptase, integrase, and protease inhibitors. In its public debut, Viva-Thera also reported that its MPER vaccine immunogens elicited antibody levels in rhesus macaques approximately five times those of the conventional HIV immunogen comparator, with antisera retaining substantial inhibition of HIV pseudovirus infection at a 1:1,000 dilution. The company is pursuing HIV prevention and cure through four modalities—vaccines, long-acting small molecules, gene therapy and cell therapy—and its gene-therapy program has completed vector construction, cell-infection experiments and CD4+ T-cell introduction in humanized mice, with live-virus infection and treatment studies in preparation.
Biotech & Genomic Medicine › AI Drug Discovery ▲Technology
Biotech & Genomic Medicine › Antiviral & Infectious-Disease Therapeutics Technology
Artificial Intelligence › AI Tooling, Data & MLOps ▲Technology
2228.HK · Technology · Positive XtalPi's AI drug design platform enabled Viva-Thera to nominate an HIV-1 MPER PCC in seven months, validating its technology.
Viva-Thera · Technology · Positive Viva-Thera nominated a preclinical HIV-1 MPER candidate and reported vaccine immunogens eliciting ~5x antibody levels in macaques.
AISB Network Launches AISB Bind to Predict Molecule Binding
The AI Structural Biology Network, powered by Apheris, launched AISB Bind, a federated initiative in which AbbVie, AstraZeneca, Bristol Myers Squibb, and Johnson & Johnson will collaboratively train an AI model to predict how small molecules bind to protein targets for virtual screening and lead optimization. The new initiative extends the network's first effort, which focused on protein-ligand structure prediction, where a co-folding model fine-tuned across more than 20,000 proprietary structures from active drug-discovery programs raised the share of high-quality predictions from 36% to 52%, outperforming public models and any model fine-tuned on a single partner's data alone. In AISB Bind, the four founding partners contribute three complementary types of data: experimentally determined structures, quantitative affinity and potency measurements, and high-throughput screening activity data, the last adding a large body of confirmed non-binders that is rarely available at industrial scale. Training runs through federated learning, so each partner's proprietary data stays within its own secure environment, with Apheris hosting the network and running the training and each partner receiving the resulting model to run and further tailor internally. Federated training begins in September 2026, with final models expected in early 2027, powered by the infrastructure of Apheris's technology partner, Amazon Web Services.
Biotech & Genomic Medicine › AI Drug Discovery ▲Technology
ABBV · Technology · Positive AbbVie is a founding partner in AISB Bind, collaboratively training an AI model to predict small-molecule binding for virtual screening and lead optimization.
AZN.LSE · Technology · Positive AstraZeneca is a founding partner in AISB Bind, contributing data to and receiving the collaboratively trained AI binding-prediction model.
BMY · Technology · Positive Bristol Myers Squibb is a founding partner in AISB Bind, contributing proprietary data to train an AI binding-prediction model for drug discovery.
JNJ · Technology · Positive Johnson & Johnson is a founding partner in AISB Bind, gaining access to a federated AI model for small-molecule binding prediction.
Twist Bioscience Partners With Lilly TuneLab for AI Antibody Data
Twist Bioscience Corporation confirmed on September 16 a strategic partnership with Lilly TuneLab, a platform created by Eli Lilly and Company, under which Twist will provide antibody characterization data services. Twist will also supply data to support AbLab, an antibody developability prediction model, along with high-throughput wet-lab data used to train and improve those models. Through the agreement, TuneLab users will be able to order Twist's antibody services using preferred Twist protocols, generating wet-lab data that can support AI-enabled antibody discovery. The companies did not disclose a minimum purchase commitment, contract value, or specific revenue guidance, and the announcement includes no rights to Lilly drug candidates, milestone payments, or royalties, so the near-term financial impact depends on how much TuneLab users ultimately purchase Twist's services. According to Insider Monkey's database, the number of hedge funds holding Twist rose to 42 in the second quarter from 30 in the first quarter, with Ark Investment Management cutting its position by 29% to $468.1 million, Farallon Capital raising its stake by 50% to $219.79 million, and DE Shaw increasing its position by 2,442% to $121.98 million, while short interest fell to 12.07 million shares as of August 31 from 14.08 million as of July 31 but remained elevated at approximately 18.20%.
Biotech & Genomic Medicine › AI Drug Discovery ▲Technology
Biotech & Genomic Medicine › Life-Science Tools & Sequencing ▲Demand
TWST · Demand · Positive Twist will provide antibody characterization data services and supply wet-lab data, with TuneLab users able to order Twist's antibody services under preferred protocols.
LLY · Technology · Positive Lilly's TuneLab platform gains Twist's antibody characterization data and wet-lab data to train its AbLab AI antibody developability model.
Novo Nordisk Partners with Anthropic to Embed Claude AI in Drug Discovery
Novo Nordisk has partnered with Anthropic to deploy Claude models and Claude Science across its research and development workflows, initially targeting specific scientific problems where AI can have the greatest impact, and will also use Anthropic's frontier models for AI-driven software development. Reuters reported that Novo already uses Claude to automate clinical-trial report generation, cutting patient-documentation timelines from months to minutes. The deal expands an AI strategy that already includes partnerships with OpenAI and Amazon Web Services, and comes as Novo works to strengthen its pipeline amid rising obesity-drug competition; its Q2 adjusted sales rose 7% at constant exchange rates to DKK 78.5 billion, while adjusted operating profit increased 11% to DKK 33.4 billion. Novo simultaneously recorded DKK 6.3 billion in non-cash impairments on pipeline assets, including DKK 4 billion related to monlunabant, underscoring the need to improve R&D productivity. The immediate financial impact remains uncertain, as the companies have not disclosed specific drug targets, development milestones, financial terms, or expected cost savings, and the arrangement begins with testing Claude in selected workflows. Novo also faces pressure from Eli Lilly in an obesity market Reuters said could exceed $100 billion annually by 2030, with Lilly's oral obesity drug having captured more than 30% of new U.S. oral-weight-loss patients by September while Novo's Wegovy pill held an estimated 90% share as of August.
China Sets 2030 Goal to Develop 25% of Global First-in-Class Drugs
Beijing has unveiled a five-year plan aimed at making China a global leader in drug innovation, with a target of developing 25% of the world's first-in-class drugs by 2030. The plan, issued in a joint notice from multiple government ministries, lays out 25 priority tasks spanning innovation capacity, research and technology, including expanded R&D, the use of AI and quantum computing in drug discovery, and the building of pharmaceutical ecosystems beyond pipelines. The government aims for the industry to reach 3.5tn yuan, or $520bn, in annual revenue by 2030, with 50 companies exceeding $1.5bn in annual revenue, and at least five Chinese drugs achieving global annual sales above $1bn. The notice singled out next-generation therapies including antibody-drug conjugates, cell and gene therapies, and CAR-T, along with vaccines and newer platforms such as mRNA, and included a section on industrialising traditional Chinese medicine. Citi analysts said the plan signals a shift from scale-driven growth toward innovation-driven, quality-oriented development, with a broad whole-value-chain policy push covering innovative drugs, medical devices, AI-driven drug discovery, and CDMO/CRO. The biomedical plan was released alongside counterparts for other strategic sectors, including integrated circuits, aerospace, the low-altitude economy, new energy storage and intelligent robotics.
Forus Raises $150 Million Series C, Valuation Hits $3 Billion
Forus, an AI network focused on accelerating medicine, has raised $150 million in a Series C funding round that lifted its valuation to $3 billion, CEO Sahir Jaggi said on NYSE Live. The round was led by BCV, or Bain Capital Ventures, an investor since the seed stage, and every existing investor reinvested, Jaggi said. The company had not planned to raise, he added, but the business expanded faster than expected as physicians referred other physicians and life science companies sought partnerships at a rising pace. The capital will go toward three priorities: expanding the Forus platform to all major specialties and sites of care, from clinics to hospital systems; deepening the AI agents and models that power that growth; and expanding the team of engineers and operators to build out the network nationwide. Forus gives every prescription its own AI agent that handles phone calls, research and paperwork for high-cost, complex medications such as those for autoimmune diseases, COPD and cancers, with the goal of placing the platform in every doctor's office in America.
NMPA Strengthens Pre-Guidance for Innovative Drugs; Penghua STAR Market Healthcare ETF Rises Over 3%
The National Medical Products Administration will advance the implementation of the pharmaceutical trial data protection system, establish market exclusivity periods for pediatric drugs and rare disease medications, and strengthen pre-guidance for innovative drugs with new targets and mechanisms. A responsible official from the NMPA stated that it will also expand the "Spring Rain Action" for transforming clinical innovations in medical devices, and formulate clinical trial and review guiding principles in frontier areas such as brain-computer interfaces. Zhongtai Securities noted that AI4S is expanding from single-point tool applications to coordinated development across data, models, wet-lab experiments, and R&D processes, and that life science upstream and CXO companies with high-quality data accumulation, automated experimental platforms, and industrial customer bases are expected to benefit continuously. As of 11:22 on September 21, 2026, the Penghua STAR Market Healthcare ETF rose 3.87%, with constituent stock HitGen up 14.54%, and Zelgen Biopharmaceuticals and Huiyu Pharmaceutical following the gains; the Penghua Hang Seng Biotech ETF rose 4.56%.
Biotech & Genomic Medicine › AI Drug Discovery ▲Technology
Biotech & Genomic Medicine › Tools, Diagnostics & CDMO ▲Demand
688222.CG · Regulation · Positive NMPA strengthening pre-guidance for innovative drugs and data protection supports HitGen's drug-discovery platform, and it was the top gainer among STAR Market healthcare constituents.
688266.CG · Regulation · Positive NMPA's new market exclusivity and pre-guidance measures for innovative drugs benefit Zelgen as an innovative biopharma constituent that rose with the sector.
688553.CG · Regulation · Positive Huiyu Pharmaceutical gained alongside peers as the NMPA's strengthened innovative-drug guidance lifted STAR Market healthcare names.
Ten ministries issue 15th Five-Year Plan for the pharmaceutical industry; Nanhua Bio gains for third straight day
On September 18, the Ministry of Industry and Information Technology, the National Development and Reform Commission and eight other departments jointly issued the 15th Five-Year Plan for the development of the pharmaceutical industry, laying out 25 key tasks in eight areas. The plan proposes that by 2030, operating revenue of Chinese pharmaceutical enterprises above designated size will exceed 3.5 trillion yuan, the innovative drug industry will grow at an average annual rate of more than 20 percent, China's share of first-in-class innovative drugs globally will exceed 25 percent, more than 200 innovative medical devices will be launched, and the number of pharmaceutical industry parks with output of at least 100 billion yuan will reach 20. Boosted by the news, innovative drug and CRO stocks rose on September 21, with Nanhua Bio gaining for a third straight day, while Harbin Pharmaceutical Group and Shandong Xinhua Pharmaceutical hit their daily limits. The same day, PCB-related shares advanced, as research reports from multiple institutions noted that upstream raw material prices have kept climbing and PCB makers have begun repricing, with the third quarter of 2026 expected to mark the start of an earnings recovery for the sector. MLCC-related shares were active, as AI-driven demand has caused shortages and sharp price surges in high-capacity models, with some spot prices soaring several-fold. Humanoid robot stocks rebounded, after drone footage suggested that the main structure of Tesla Optimus's dedicated production line in Texas may be nearing completion; the line is scheduled to begin production in 2027 with an annual capacity target of 10 million units.
UBS Flags AI Science Shift as Investment Theme After OpenAI Proof
UBS Wealth Management says artificial intelligence is moving beyond text generation into scientific research, opening investment opportunities across AI infrastructure, pharmaceuticals, nuclear fusion, industrial materials and utilities. The shift was highlighted by OpenAI's recent mathematical proof related to the Navier-Stokes equations, a centuries-old fluid dynamics problem and one of seven Millennium Prize Problems, which OpenAI tackled using 10,000 autonomous AI agents working in parallel for 88 hours before formalizing the proof with Lean, a system for machine-checked mathematical validation. In pharmaceuticals, multi-agent AI systems can simulate millions of protein variations in the cloud, and more than 170 AI-designed programs are already in development or clinical evaluation, including Phase III trials. In nuclear fusion, reinforcement-learning systems can predict plasma disruptions around 200 milliseconds before they occur and adjust magnetic coils thousands of times per second, while AI models in materials science can test millions of elemental combinations daily in search of properties for lighter, higher-density batteries, lower-heat computing hardware and potential room-temperature superconductors. The broader investment case centers on AI becoming a tool for automating scientific research rather than simply generating content, with companies exposed to AI infrastructure, pharmaceuticals, industrial materials and utilities positioned to benefit as these technologies move toward commercial applications.
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AI Drug Discovery▲
NAVER D2SF Backs ImpriMed in $10 Million Series A2 Bridge Round
NAVER D2SF, NAVER's in-house corporate venture arm, has invested in Silicon Valley precision medicine company ImpriMed, joining ImpriMed's $10 million Series A2 bridge round. The round was led by LB Investment, with participation from new investors NAVER D2SF, Samsung Securities, and Alois Ventures, plus follow-on investments from existing investors BonAngels and Han River Partners; it follows ImpriMed's $23 million Series A in 2023. ImpriMed combines ex vivo analysis of patient-derived live cancer cells with genomic, immunophenotypic, and clinical data through its xCellSense platform, and is developing AI models trained on more than 3.5 million data points. The company is preparing to commercialize products for blood cancers and blood infection, targeting FDA clearance and CLIA certification by Q1 2027 for an initial U.S. launch, while in South Korea its multiple myeloma prognosis and therapy-response software has been designated an Innovative Medical Device by the Ministry of Food and Drug Safety. ImpriMed was co-founded by CEO Sungwon Lim and CTO Jamin Koo, and its human healthcare expansion is supported by veterinary precision oncology work covering more than 27,000 tests for canine and feline lymphoma, used by over 600 veterinary hospitals across the United States, Canada, the United Kingdom, France, and South Korea.
Anthropic Establishes Biology Research Lab to Pursue AI-Driven Drug Development
US artificial intelligence developer Anthropic has established a biology research institute as it moves toward full-scale drug development using AI technology. According to two people familiar with the matter, the company has opened a wet lab experimental facility in the San Francisco Bay Area, aiming to develop treatments for rare diseases, and its biological research goes beyond the realm of computer simulation. Eric Kauderer-Abrams, head of the life sciences division, confirmed to Reuters on the 15th that the company operates a wet lab, saying its mission is to develop powerful AI that benefits the world, and that it sees the greatest potential especially in the life sciences field. A public relations representative later explained that the institute is not specifically aimed at drug discovery, but declined to comment further. Kauderer-Abrams said efforts to use AI to automate the execution of experimental work are still in their early stages, but could bring significant reductions in working time across many different processes, and that the company is approaching how to use it carefully and thoughtfully in order to improve its models and minimize risk in ways that facilitate and accelerate drug development. The diseases Anthropic is working to develop treatments for, and its progress, remain unclear.
Big Picture Bio Launches With £2.2 Million to Design Cancer Combination Therapies
Big Picture Bio Ltd. has been founded in London to identify, design and optimise promising cancer combination therapies using a generative world model of how tumours, immune cells and surrounding tissue interact across disease sites and patient subgroups. The company has closed a £1.5 million, or roughly $2 million USD, pre-seed funding round co-led by Kadmos Capital and Exceptional Ventures, with participation from Gloucester Ventures and angel investor John White. That pre-seed round is in addition to £700,000, or roughly $950,000 USD, in non-dilutive funding from Innovate UK through its Investor Partnerships Programme, bringing total funding to £2.2 million, or roughly $3 million USD, to take its first designed drug combinations from in silico design into wet lab validation. Big Picture Bio was founded by Dr Kerstin Papenfuss, CEO and co-founder, and Dr Mark Hammond, CTO and co-founder, both veterans of Deep Science Ventures, and is advised by Dr Laura Rosenberg and Dr Duncan Young of AstraZeneca, Dr Garry Pairaudeau of DaltonTx and former CTO of Exscientia, and Dr Christian Dillon of PhoreMost. The company said its platform has been validated against real-world clinical outcomes presented at ASCO and correctly predicted the failure of Regeneron's recent fianlimab trial.
Biotech & Genomic Medicine › AI Drug Discovery ▲Technology
Biotech & Genomic Medicine › Oncology Therapeutics Technology
Big Picture Bio Ltd. · Capital · Positive Big Picture Bio launched with £2.2 million in total funding (£1.5M pre-seed plus £700K Innovate UK grant) to advance its cancer combination therapies.
REGN · Technology · Negative Big Picture Bio's platform correctly predicted the failure of Regeneron's fianlimab trial, a negative read on that drug program.
Causaly Brings Agentic Scientific Research Into Microsoft Copilot
Causaly announced an expansion of its collaboration with Microsoft that makes its agentic scientific research available directly inside Microsoft Copilot. Enterprise life sciences R&D teams can now access Causaly within their existing Microsoft 365 workflows, including the Copilot app and Microsoft Teams, where users invoke the agent from its menu or by mentioning Causaly in a conversation. The integration adds a vertical scientific workflow layer to Copilot, orchestrating end-to-end research that surfaces prior science, reasons over biological mechanisms, and synthesizes evidence into cited answers, with every response carrying traceable references back to peer-reviewed literature, biomedical databases, and Causaly's proprietary Bio Graph and Pipeline Graph knowledge graphs. The move builds on the collaboration the two companies announced at Microsoft Build 2026 in June, which paired Causaly's scientific interpretation with Microsoft Discovery's enterprise scientific platform. Causaly co-founder and CEO Yiannis Kiachopoulos said the extension puts governed, provenance-first scientific reasoning inside the same interface used across research, development, medical, and commercial functions in biopharma, while Microsoft 365 Copilot principal product manager Chantrelle Neilsen called the integration a strong example of specialized enterprise agents grounded in evidence and available where the work happens. Causaly is available on the Microsoft Marketplace.
Artificial Intelligence › AI Applications & Copilots ▲Technology
Artificial Intelligence › Agentic AI & Autonomous Workflows ▲Technology
Biotech & Genomic Medicine › AI Drug Discovery Technology
Causaly · Demand · Positive Expanded Microsoft collaboration makes Causaly's agentic scientific research available inside Copilot and Microsoft 365 workflows, broadening its enterprise reach.
MSFT · Technology · Positive Causaly's agentic scientific research is integrated into Microsoft Copilot, adding a vertical scientific workflow layer to the product.
Orbis Medicines and Novo Nordisk Sign Up to USD 1.4 Billion Drug Discovery Deal
Orbis Medicines has entered a strategic collaboration and license agreement with Novo Nordisk to discover and develop next-generation oral macrocycle therapeutics for cardiometabolic diseases. Under the terms, Orbis Medicines is eligible to receive up to USD 1.4 billion in upfront and potential development and commercial milestone payments, plus tiered royalties on future product sales, and Novo will also make a strategic investment in Orbis Medicines. The collaboration will use Orbis Medicines' proprietary nGen platform, which integrates generative AI with high-throughput synthesis to design orally bioavailable macrocycles called nCycles. Morten Graugaard, chief executive officer of Orbis Medicines, said the partnership could unlock a new generation of oral medicines for cardiometabolic diseases, while Brian Vandahl, senior vice president of Therapeutics Discovery at Novo, said the collaboration could expand the possibilities of macrocycle therapeutics. Orbis Medicines, based in Copenhagen, Denmark and Lausanne, Switzerland, has raised EUR 116 million in venture funding to date, including a EUR 90 million Series A round led by NEA.
Biotech & Genomic Medicine › Metabolic, Diabetes & Obesity ▲Demand
Biotech & Genomic Medicine › AI Drug Discovery Technology
NVO · Demand · Positive Novo Nordisk signs a USD 1.4B collaboration/license deal with Orbis to discover and develop next-generation oral macrocycle therapeutics for cardiometabolic diseases.
Orbis Medicines · Demand · Positive Orbis Medicines enters a strategic collaboration and license agreement with Novo Nordisk, eligible for up to USD 1.4B in milestones plus royalties and a strategic investment.
Twist Bio and Ginkgo Bioworks Rise on Lilly TuneLab Agreements
Twist Bioscience and Ginkgo Bioworks traded higher on Wednesday after each announced agreements with Lilly TuneLab, a collaborative drug discovery platform established by Eli Lilly. Under its agreement, Twist Bioscience said it will provide antibody characterization data services to TuneLab companies accessing AI and machine learning drug discovery models trained on Lilly-owned research data. CEO Emily Leproust said Twist has the scale and high-throughput capabilities to generate consistent and reliable antibody characterization data these models need to be trained on. Ginkgo Bioworks, through its Ginkgo Datapoints offering, will provide discovery data generation services to TuneLab users. John Androsavich, General Manager at Ginkgo Datapoints, said layering on Ginkgo's ability to quickly generate high-quality, AI-ready datasets at any scale should let TuneLab participants close the loop between digital design and biological reality faster than ever before.
Biotech & Genomic Medicine › Life-Science Tools & Sequencing ▲Demand
Biotech & Genomic Medicine › AI Drug Discovery Technology
DNA · Demand · Positive Ginkgo Datapoints will provide discovery data generation services to Lilly TuneLab users, a concrete new customer/order channel.
TWST · Demand · Positive Twist will provide antibody characterization data services to TuneLab companies, a concrete new service demand channel.
HHS to unveil SPECTRA autism research initiative using AI
The Department of Health and Human Services is expected to unveil an autism research initiative, named SPECTRA, that will use artificial intelligence to better understand the disorder and find ways to treat it earlier. According to a draft document obtained by Bloomberg, the program will evaluate data and, in areas of uncertainty, help determine "the missing biology needed to treat earlier and prevent avoidable illness." Information on spending for the program was not immediately available. The document states that autism could be discovered earlier, leading to better treatment, through more thorough testing and at-home monitoring with AI, and that wearables could also enter the picture. SPECTRA will run under the watch of the Advanced Research Projects Agency for Health, which, according to its mission statement, "supports the development of high-impact solutions to society's most challenging health problems." In late August, an advisory panel to HHS met to discuss a draft plan that would significantly increase funding for medical care and other areas related to autism.
Alphabet's 2026 EPS Estimate Jumps to $20.60 From $14.23 in 90 Days
Alphabet's 2026 earnings-per-share estimate has climbed from $14.23 ninety days ago to $20.60 today, one of the sharpest upward revisions in mega-cap tech, as the company's AI story finally shows up in the numbers. Google Cloud grew 82% in the second quarter, Gemini Enterprise is deployed at nearly 90% of the Fortune 100, and CEO Sundar Pichai told investors Alphabet is still in a supply constraint environment. The stock has risen 42.62% over the past year and 9.36% year to date, recently brushing a 52-week high of $403.96, while the Street's consensus 12-month target sits at $422.34 with 13 strong buys, 44 buys, and just 5 holds. Analysts see revenue reaching roughly $613 billion in 2027 against $498 billion this year, and Alphabet has beaten consensus in 11 consecutive quarters while posting 12 straight quarters of double-digit revenue growth. The bull case rests on converting a $514 billion cloud backlog, with management guiding to recognize just over 50% as revenue in the next 24 months, plus TPU systems revenue that Pichai said will be largely realized in 2027, Gemini monetization across 950 million monthly active app users and more than 1 billion AI Mode users, and optionality from Waymo's 500,000-plus weekly autonomous rides and Isomorphic Labs' $2 billion raise. Risks include negative second-quarter free cash flow of $5.86 billion after $44.92 billion of capital expenditure, long-term debt of $98.2 billion, and 2026 capital spending guided at $175 billion to $185 billion.
Robotics & Physical AI › Robotaxi Operators & Platforms ▲Demand
Biotech & Genomic Medicine › AI Drug Discovery ▲Capital
Artificial Intelligence › AI Compute Cloud & Neoclouds ▲Demand
GOOG · Capital · Positive 2026 EPS estimate jumped to $20.60 from $14.23 in 90 days, with consensus target $422.34 and 13 strong buys/44 buys.
GOOG · Demand · Positive Google Cloud grew 82% in Q2, Gemini Enterprise deployed at nearly 90% of Fortune 100, and a $514B cloud backlog with over 50% to be recognized in 24 months.
Isomorphic Labs · Capital · Positive Isomorphic Labs raised $2 billion, cited as optionality in Alphabet's bull case.
Ginkgo Datapoints Partners with Lilly TuneLab to Link AI Drug Discovery Models to Lab Data
Ginkgo Bioworks announced that its Ginkgo Datapoints offering has entered a new agreement with Lilly TuneLab, the collaborative AI/ML drug discovery platform created by Eli Lilly and Company. Under the deal, Ginkgo Datapoints will provide discovery data generation services, including small molecule developability (ADME) and antibody developability testing, to companies participating in TuneLab. John Androsavich, General Manager at Ginkgo Datapoints, said the combination of Ginkgo's automation and TuneLab's collaboration platform aims to accelerate next-generation therapeutic development across the industry, letting participants close the loop between digital design and biological reality faster than ever before. Ginkgo said its antibody and small molecule developability screening can turn around results in ML-ready formats that plug directly into TuneLab's predictive models, closing the loop between an AI-generated hypothesis and validated lab data in days rather than months. The standardized assay protocols are expected to help AI/ML models learn more efficiently, and new TuneLab members can now submit Datapoints-generated data to access additional platform model benefits. Lilly TuneLab is part of Lilly Catalyze360, alongside Lilly Ventures, Lilly Gateway Labs, and Lilly ExploR&D.
Biotech & Genomic Medicine › AI Drug Discovery ▲Technology
Biotech & Genomic Medicine › Tools, Diagnostics & CDMO ▲Demand
Artificial Intelligence › AI Tooling, Data & MLOps Technology
DNA · Demand · Positive Ginkgo Datapoints signs agreement with Lilly TuneLab to provide discovery data generation services to TuneLab participants, a concrete new business deal.
LLY · Technology · Positive Lilly's TuneLab AI/ML drug discovery platform gains Ginkgo's ML-ready lab data generation, strengthening its predictive models and platform offering.
ByteDance's Spun-Off AI Drug Discovery Unit Raises $290 Million at $1.5 Billion Valuation
ByteDance has completed a $290 million fundraising round for its AI drug discovery unit that was spun off from the group, two people familiar with the matter said on the 16th. Shanghai-based Anew Labs reached a $1.5 billion valuation with its first external funding round. According to the sources, the round was led by HSG, IDG Capital, and Hillhouse Investment, with 5Y Capital as a co-lead investor. ByteDance and the investors declined to comment. The company said it spun off the unit because AI drug discovery is an industry different from the group's core business, and separating it would better support its long-term development; after the fundraising, ByteDance will continue to hold a 56 percent stake.
Biotech & Genomic Medicine › AI Drug Discovery ▲Capital
Anew Labs · Capital · Positive Anew Labs raised $290M in its first external round, reaching a $1.5B valuation.
ByteDance · Capital · Positive ByteDance spun off its AI drug discovery unit, which raised $290M at a $1.5B valuation while ByteDance retains a 56% stake.
5Y Capital · Capital · Positive 5Y Capital was a co-lead investor in Anew Labs' $290M round.
Hillhouse Investment · Capital · Positive Hillhouse Investment led the $290M funding round for Anew Labs.
Redwire Expands Microgravity Platform With 11 ISS Payload Facilities
Redwire Corporation is expanding its microgravity capabilities beyond traditional space missions into scientific research, biotechnology and advanced manufacturing. The company has built a growing microgravity platform with 11 active payload facilities on the International Space Station as of Dec. 31, 2025, and has launched 42 Pharmaceutical In-space Laboratory – Bio-crystal Optimization eXperiment, or PIL-BOX, payloads. During 2025, Redwire entered a licensing agreement with ExesaLibero Pharma under which it is eligible to receive royalties from commercial sales of resulting pharmaceutical products. Bristol Myers Squibb and Eli Lilly have both partnered with Redwire on PIL-BOX missions to study pharmaceutical molecules and crystal growth in microgravity. The Zacks Consensus Estimate for 2026 and 2027 earnings per share suggests year-over-year growth of 57.32% and 40%, respectively, while Redwire trades at a forward 12-month price-to-sales of 4.92X versus an industry average of 2.29X.
Space Economy › In-Space Manufacturing & Commercial Stations ▲Demand
Space Economy › Satellite & Spacecraft Manufacturing ▲Technology
Biotech & Genomic Medicine › AI Drug Discovery Technology
RDW · Capital · Positive Redwire's licensing agreement with ExesaLibero Pharma makes it eligible for royalties from commercial sales of resulting pharmaceutical products.
RDW · Technology · Positive Redwire expanded its microgravity platform to 11 active ISS payload facilities and 42 PIL-BOX launches, advancing its research and manufacturing capabilities.
ExesaLibero Pharma · Capital · Positive ExesaLibero Pharma entered a licensing agreement with Redwire under which Redwire receives royalties from commercial sales of resulting pharmaceutical products.
BMY · Technology · Neutral Bristol Myers Squibb partnered with Redwire on PIL-BOX missions to study pharmaceutical molecules and crystal growth in microgravity, but no outcome or financial impact is stated.
LLY · Technology · Neutral Eli Lilly partnered with Redwire on PIL-BOX missions to study pharmaceutical molecules and crystal growth in microgravity, but no outcome or financial impact is stated.
Tempus Launches 100,000-Genome Multimodal Dataset Initiative
Tempus AI announced an initiative to build a research platform containing 100,000 whole genomes linked to longitudinal clinical information over the next several years, with a long-term goal of reaching one million genomes. The company said the effort will create the first de-identified multimodal whole-genome sequencing dataset built around disease populations and patient outcomes and specifically optimized for AI-driven research. The new dataset will be integrated into Tempus' existing de-identified multimodal data environment, where researchers can access genomic information alongside clinical histories, imaging, pathology and patient outcomes, and analyze it through Tempus Lens without moving datasets between systems. Development is already underway and the initial dataset is available through Tempus' Early Adopter Program, with additional members onboarded in waves and general availability planned for mid-2027. Founder and CEO Eric Lefkofsky said adding whole genome data linked to longitudinal outcomes gives researchers a richer foundation to build AI models and ultimately improve patient care.
Biotech & Genomic Medicine › Diagnostics & Precision Testing ▲Technology
Artificial Intelligence › AI Tooling, Data & MLOps ▲Demand
Biotech & Genomic Medicine › Life-Science Tools & Sequencing ▲Demand
Biotech & Genomic Medicine › AI Drug Discovery ▲Technology
Artificial Intelligence › AI Applications & Copilots ▲Technology
TEM · Technology · Positive Tempus launches a 100,000-genome multimodal dataset initiative optimized for AI-driven research, expanding its product/data platform.