Align Technology IncImpact on assets 3
Aging Population▲ · 1 stocks
Align Technology IncALGN
Mentioned
Biotech & Genomic Medicine▲ · 1 stocks
Johnson & JohnsonJNJ
Mentioned
Health Care▲ · 1 stocks
Sonova H AgSOON
Mentioned
Theme Impact 2
Off-coverage companies 2
Neuromod DevicesPrivate▲ Positive
Demandrelevance
Neuromod adds senior commercial and channel leaders to scale adoption of its Lenire tinnitus treatment device globally.
Johnson & Johnson VisionPrivate± Mixed
relevance
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Dental Corporation, or D, moves from mai to trade on SET on October 1, 2026
Dental Corporation Public Company Limited, or D, has met the criteria of the Stock Exchange of Thailand and will move from the Market for Alternative Investment, or mai, to trade on the SET in the Services industry group, Medical business sector, starting October 1, 2026, after more than 9 years listed on mai. Chief Executive Officer Pornsak Tantapakul, together with the company's board and executives, joined in congratulating the occasion. The company stated that the move to the SET reflects the organization's growth and potential, from its beginnings as a Thai family business to a listed company in the capital market, and that over the past 9 years it has used funds raised to expand its business, generating growth in revenue, net profit, and shareholders' equity. The Dental Corporation group operates a full-service dental business, covering dental hospitals, the Bangkok International Dental Hospital, or BIDH, dental centers, Smile Signature dental clinics, and Dental Planet dental clinics, as well as Dental Vision Company Limited, a subsidiary that distributes dental materials and equipment.
About megatrends
Aging Population › Hearing / Vision / Dental ▲Capital
Aging Population › Dental & Clear Aligners Capital
D.BK · Capital · Positive Dental Corporation moves from mai to trade on the SET, reflecting its growth in revenue, net profit, and shareholders' equity.
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SpyGlass Pharma Acquires Advanced Vision Science for $13 Million
SpyGlass Pharma, Inc. announced today it has acquired all outstanding shares of common stock of Advanced Vision Science, Inc., an ophthalmic medical device company and manufacturer of intraocular lenses and lens materials, for approximately $13 million in cash. AVS was a wholly owned subsidiary of Santen Pharmaceutical Co., Ltd. and is the current supplier of the intraocular lens used in SpyGlass Pharma's two Phase 3 registrational trials evaluating the BIM-IOL System. The acquisition secures scalable commercial intraocular lens manufacturing capacity for SpyGlass Pharma's lead product candidate and accelerates its pathway to adding premium lens options into its intraocular-lens-based drug delivery system. Under the agreement, AVS will be the exclusive manufacturer and supplier of several types of intraocular lenses to Santen for commercialization in Japan, and will continue to license its glistening-free hydrophobic acrylic lens material to Bausch + Lomb for use in the enVista intraocular lens line and manufacture products for other global intraocular lens companies. SpyGlass Pharma said it intends to continue supporting AVS customers and licensees utilizing their proprietary intraocular lens material technology, such as Santen, Bausch + Lomb, and other global intraocular lens companies.
About megatrends
Aging Population › Vision & Eye Care ▲Supply
SGP · Supply · Positive SpyGlass acquires AVS, securing scalable commercial intraocular lens manufacturing capacity for its lead BIM-IOL product candidate.
Advanced Vision Science, Inc. · Capital · Positive Advanced Vision Science is acquired by SpyGlass Pharma for approximately $13 million in cash.
4536.JP · · Neutral Santen sold its AVS subsidiary for ~$13M but retains AVS as exclusive manufacturer/supplier of intraocular lenses for commercialization in Japan.
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Bernstein names Sonova, Alcon as top European medtech picks for H2
Bernstein has named Sonova as its short-term top pick and Alcon as its preferred long-term idea in a new H2 playbook for European medtech, assigning both "outperform" ratings with price targets of CHF 275 and CHF 76.15, respectively. Sonova, the world's No. 1 player in the $7.7 billion hearing aid wholesale market with roughly a 25% unit share, is expected to benefit from a multi-pronged growth setup into its H1 2026/27E results in November, with Bernstein forecasting H1 wholesale organic growth of 10.1% versus consensus at 8% and Group organic growth of 6.5% versus consensus of 4.9%. The bull case rests on continued strength from the EON Sphere launch, further share gains at Costco, where the Infinio-based device only entered the channel in March 2026, and another seven months of tailwind from Virto R hearing aid sales, plus a sharp H2 improvement in the Cochlear Implant business and accelerating M&A contribution in Retail as rivals Demant and Amplifon remain financially constrained. Bernstein's core EBIT estimates sit 5-8% above consensus across 2026/27E-2028/29E. On Alcon, the dominant ophthalmology player holding #1 or #2 positions across most of its sub-markets, Bernstein argues investor sentiment on the intraocular lens and consumables businesses has become "overly negative" and that the pressure is "largely transitory," expecting implantables growth to accelerate to 4% in 2027. Bernstein's constant-currency revenue growth estimates run 38-112 bps above consensus for 2026E-2028E, with core EPS estimates 1-9% higher, and at roughly 17x NTM P/E it sees an attractive entry point into what it calls a "multi-year compounding business."
About megatrends
Aging Population › Hearing (aids & cochlear implants) ▲Demand
Aging Population › Vision & Eye Care ▲Demand
ALC.SW · Capital · Positive Bernstein names Alcon its preferred long-term European medtech pick with an outperform rating and CHF 76.15 price target, arguing negative sentiment is overdone.
SOON.SW · Capital · Positive Bernstein names Sonova its short-term top pick with an outperform rating and CHF 275 price target, citing above-consensus EBIT estimates.
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CVS Health Raises 2026 Revenue and Earnings Guidance
CVS Health now projects 2026 revenues of at least $414 billion, up from its earlier projection of at least $405 billion, and boosted adjusted earnings guidance to $7.90-$8.10 from $7.30-$7.50. The company said it still faces reimbursement pressure across its government, retail pharmacy and PBM businesses, and that the 2027 Medicare Advantage payment update is insufficient to fully offset underlying medical cost trends. In the second quarter, same-store front-store sales rose just 1% year over year, while the Pharmacy & Consumer Wellness segment's growth was offset by regulatory-related price reductions, generic introductions and pharmacy reimbursement pressure. In a peer update, Align Technology recorded an estimated $37.5 million liability, including interest, after the U.K. Upper Tribunal in July 2026 overturned the prior VAT-exemption ruling for clear aligners, and will apply 20% VAT to applicable U.K. Invisalign aligners and Vivera retainers from Sept. 7, 2026, without changing list prices. Cardinal Health said a prolonged conflict in Iran could move its Global Medical Products and Distribution segment toward the lower end of its $200 million to $220 million segment profit range.
About megatrends
Aging Population › Dental & Clear Aligners ▼Regulation
CVS · Capital · Positive CVS raised its 2026 revenue guidance to at least $414 billion and adjusted EPS guidance to $7.90-$8.10.
ALGN · Regulation · Negative U.K. Upper Tribunal overturned the VAT-exemption ruling for clear aligners, imposing 20% VAT on applicable U.K. Invisalign aligners and Vivera retainers, creating an estimated $37.5 million liability.
CAH · Geopolitics · Negative A prolonged conflict in Iran could push its Global Medical Products and Distribution segment toward the lower end of its $200-220 million profit range.
3
Apple unveils Apple Watch Series 12 and Ultra 4 with new health features
Apple has announced its most advanced health and fitness experience yet, introducing the Apple Watch Series 12 and Apple Watch Ultra 4 with a new Health Sensing System that delivers the most accurate heart rate sensing in a wearable, along with a redesigned Health app powered by Apple Intelligence. The new watches measure heart rate every five seconds and HRV as often as every five minutes, 24 times more frequently, and introduce a readiness score from 0 to 10 with recommendations like Recover or Go For It. The redesigned Health app, coming later this year with iOS 27, adds an Insights tab and a Longevity tab featuring Health Age, which compares users' metrics to their chronological age. Users can also schedule and purchase lab tests covering over 50 biomarkers for $119 at approximately 2,000 Quest Diagnostics locations in the U.S., and new movement assessments use the iPhone camera and Apple Watch for at-home evaluations. The watches also support perimenopause and menopause tracking, and watchOS 27 will be available starting September 14 for Apple Watch Series 9 or later, Apple Watch SE 3, and Apple Watch Ultra 2 or later.
About megatrends
Aging Population › Hearing / Vision / Dental Technology
Longevity & Life Extension › Longevity Diagnostics & Aging Clocks ▲Demand
Longevity & Life Extension › Longevity Clinics & Healthspan Services ▲Demand
Aging Population › Medical Devices for the Aging Body Technology
AAPL · Technology · Positive Apple unveils new Apple Watch models with advanced health features and AI-powered Health app.
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Taiwan Faces Demographic Crisis, Population Expected to Drop 48% to 12.15 Million by 2075
Bloomberg reports that Taiwan's population may decline to about 12.15 million by 2075, a drop of roughly 48% from 2026 levels, amid a continued decrease in births and young population, while the number of elderly rises significantly, posing long-term challenges to the labor market, economy, and defense capabilities. Estimates from Taiwan's National Development Council (NDC), based on household registration data, indicate that the working-age population will shrink by nearly two-thirds over the next 50 years. By 2075, the population aged 0-14 will be only 585,000, the working-age population (15-64) will be about 5.13 million, and those aged 65 and above will reach 6.43 million, meaning the elderly will outnumber the working-age population and account for more than half of the total population. These figures reflect risks after the population peaked at 23.6 million in 2019, and could also affect Taiwan's security, as the military still relies partly on conscription amid threats from China.
About megatrends
Aging Population › Senior Care ▲Demand
Aging Population › Medical Devices for the Aging Body ▲Demand
Aging Population › Chronic-Disease Pharma Franchises ▲Demand
Aging Population › Hearing / Vision / Dental ▲Demand
Aging Population › Home Healthcare & Hospice ▲Demand
Aging Population › Mobility Aids & Assistive Technology ▲Demand
Aging Population › Retirement Income & Annuities ▲Demand
Aging Population › Dialysis & Renal Care ▲Demand