← Back

Corvus Pharmaceuticals Inc

Corvus Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company that develops product candidates targeting proteins critical to immune cell maturation and function. Its lead candidate, soquelitinib (CPI-818), is a selective covalent inhibitor of interleukin-2 inducible T cell kinase (ITK) being evaluated in a Phase 1b/2 trial for peripheral T cell lymphoma, atopic dermatitis, hidradenitis suppurativa, autoimmune lymphoproliferative syndrome, solid tumors, and asthma. The company is also developing ciforadenant (CPI-444), an oral A2A receptor antagonist in Phase 2 for first-line renal cell cancer, and mupadolimab (CPI-006), a humanized monoclonal antibody in Phase 1 for non-small cell lung cancer. It has license agreements with Monash University for CXCR2 antibodies, with Vernalis (R&D) Limited for adenosine receptor antagonists including ciforadenant, and with Scripps for mupadolimab. Incorporated in 2014, Corvus is based in South San Francisco, California.

Price · split & dividend adjusted
News & notes moving CRVS
United StatesChina
Biotech & Genomic Medicine▲

Corvus Pharmaceuticals Advances Soquelitinib Across Five Diseases

Corvus Pharmaceuticals reported second-quarter 2026 results highlighting progress for its oral ITK inhibitor soquelitinib, now in testing across five diseases. In a Phase 1 atopic dermatitis trial, 75% of patients on 200 milligram twice-daily dosing achieved EASI-75 at 8 weeks versus 20% on placebo, with benefits persisting after dosing stopped. The company plans a roughly 200-patient Phase 2 SEERA-1 trial with enrollment completing in early 2027 and results the following quarter. Corvus ended the quarter with $215 million in cash and marketable securities, up from $56.8 million at the end of 2025, after raising $189 million in a first-quarter follow-on offering, funding operations into the second quarter of 2028. R&D expenses rose to $16 million from $7.9 million a year earlier, and the net loss widened to $18 million from $8 million. A Phase 3 trial in relapsed or refractory peripheral T-cell lymphoma will undergo a futility analysis around the first quarter of 2027 with no public data release. Corvus also invested another $5 million in China-based partner Angel Pharmaceuticals as part of a $13.5 million financing round, with Angel's first 24-patient cohort expected to finish enrolling in September. Hedge fund holders increased from 19 to 36, while short interest stands at 24.74% of the float.
About megatrends
Biotech & Genomic Medicine › Autoimmune & Immunology Therapeutics ▲Technology
CRVS · Technology · Positive Positive Phase 1 atopic dermatitis data and progress across five diseases for soquelitinib.
Angel Pharmaceuticals · Capital · Positive Corvus invested additional $5 million in Angel Pharmaceuticals, supporting its development.
Read original ↗
Insider Monkey·50dRead more →
Biotech & Genomic Medicine▲

Renal Cancer Pipeline Report 2026: Over 80 Drugs and 75+ Companies Analyzed

A new report on the renal cancer pipeline for 2026 provides comprehensive insights into over 75 companies and more than 80 pipeline drugs. The analysis covers drug profiles across clinical and nonclinical stages, including assessments by product type, stage, route of administration, and molecule type. Key emerging drugs include Exelixis' zanzalintinib in phase III for non-clear cell renal cell carcinoma, Merck's quavonlimab combined with pembrolizumab in phase III, and Corvus Pharmaceuticals' ciforadenant in phase II. The report also details collaborations, acquisitions, and licensing activities, and highlights unmet needs and future perspectives in renal cancer therapeutics.
About megatrends
Biotech & Genomic Medicine › Oncology Therapeutics Competition
EXEL · Technology · Positive Zanzalintinib is highlighted as a key emerging drug in phase III for non-clear cell renal cell carcinoma.
CRVS · Technology · Positive Ciforadenant is highlighted as a key emerging drug in phase II for renal cancer.
MRK · Technology · Positive Quavonlimab combined with pembrolizumab is highlighted as a key emerging drug in phase III for renal cancer.
Read original ↗
GlobeNewswire·95dRead more →
CRVS▲

Corvus Pharmaceuticals Director Buys 21,700 Shares

Corvus Pharmaceuticals director David Scott Moore acquired 21,700 common shares through an option exercise on June 11, 2026, according to an SEC filing. The transaction was valued at approximately $250,236 based on a weighted average purchase price of $11.53 per share. Following the purchase, Moore directly holds 21,700 shares worth about $252,000 at the June 11 closing price of $11.60, representing less than 0.03% of the company. He also received 15,000 stock options with an exercise price of $11.60 that vest in about a year. Corvus Pharmaceuticals, a clinical-stage immuno-oncology company, has seen its stock price rise 217% over the past year, with a market capitalization of $1.07 billion as of June 22, 2026.
CRVS · Capital · Positive Director's insider purchase signals confidence in the company's prospects.
Read original ↗
The Motley Fool·105dRead more →