Hilleman Labs to supply Bundibugyo Ebola vaccine for clinical trials

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Hilleman Laboratories, a Singapore-based joint venture between Merck and Wellcome, is preparing to manufacture doses of an experimental vaccine against the Bundibugyo strain of Ebola for clinical trials, supported by up to $8.5 million in funding from the Coalition for Epidemic Preparedness Innovations. The candidate uses the recombinant vesicular stomatitis virus platform, the same backbone as the licensed Zaire ebolavirus vaccine, and aims to address the lack of an approved vaccine for Bundibugyo as cases rise in the Democratic Republic of Congo. Hilleman will finalize the manufacturing process and produce clinical trial supplies using starting material generated by IAVI with CEPI support, while Merck acts as a technical adviser contributing proprietary expertise on the platform. If early-stage trials succeed, the partners plan to transfer the technology to large-scale manufacture for rapid and affordable supply in outbreak regions, with an updated process backed by up to $30 million in CEPI funding designed to improve yields and thermostability, potentially lowering costs and enabling refrigerated storage for several months. The initiative is part of CEPI's broader 100 Days Mission to accelerate vaccine development against epidemic threats.

Impact on assets 2

Biotech & Genomic Medicine▲ · 1 stocks
Merck & Company Inc
MRK
▲ PositiveTechnologyrelevance

Merck acts as technical adviser, contributing proprietary platform expertise; successful trials could lead to manufacturing transfer and royalties.

Critical Materials & Supply Chain▲ · 1 stocks

Theme Impact 1

Off-coverage companies 1

Hilleman LaboratoriesPrivate▲ Positive
Technologyrelevance

Hilleman Labs is the central subject, receiving funding to manufacture and develop the vaccine candidate.

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